The wide variety of trigger conditions available allow you to react to very specific situations.
For example, you receive automated emails from a back-office system. Add a trigger that upon creating a ticket in HelpSpot for those emails automatically closes them so they're recorded but not in the agent's inbox.
Or, when any request is updated to change the category from 'technical support' to 'professional services' assign the request
to the head of services, email a notification to the help desk manager, and set a
custom field value to indicate an upsell to professional services occurred.